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A word about laminins (part 1)

This entry was posted on Oct 06 2009

(update 12/10/09: read part 2 here)

Laminin, a quiet and generally unreported molecule, is astonishingly popular in evangelical Christian circles. A casual search on google carries a plethora of links relating to laminin. In America you can buy shirts boldly proclaiming laminin. It’s the topic of numerous chain emails and social media spreads. Even in Auckland, New Zealand, I have once heard this humble glycoprotein being proudly expounded from the pulpit.

I’d say that the renown of this particular molecule has partly been fueled by this particular presentation by evangelist Louie Giglio:

Many Christians have since then leapt onto this observation as the fulfilment of Colossians 1:17. Some go so far as to proclaim this cell-adhesion molecule as an ad hoc gospel. However, I have some genuine concerns for the way this particular section of Colossians has become exegeted in the majority of the laminin-loving blogosphere, and the ramifications of this for thinking, believing Christians.

What follows are some thoughts and observations.

1. A molecule’s illustrated shape varies from its real-life shape.

I’m a medical writer by trade, so when Louie Giglio flashed the cross-shaped diagram of laminin on-screen I recognised it as a scientific illustration. Those who study chemistry and molecular biology will understand that diagrams like this don’t actually represent accurate protein shapes, but are drawn out to help the scientist or student delineate the main components of a biological structure.

You then also have to take into account that proteins move and change their conformation frequently. Giglio’s electron microscope photograph of the laminin in real life is at best, a chance capture of laminin’s genuine shape at and worst, a misrepresentation of the truth – consider the following thoughts by author of the “Exploring Creation…” textbooks, Dr Jay E. Wile:

Indeed, the electron microscope picture that Louie Giglio gives in his sermon represents just one possible shape for laminin. Consider this image, which contains two different electron microscope images of laminin:

Two TEMS of laminin

It looks to me like the bottom one is the one that Louie Giglio used, rotated 90 degrees. This makes me wonder if he intentionally edited out the other image. In any event, the top one shows what any molecular biology graduate student would know: proteins change conformation in order to do their job. The shape at any given time is most likely transitory.

The impression that Giglio gives that all these molecules in our body just sit around being cross-shaped is actually far from reality. In fact, I’m more encouraged that God created laminins to be far more complex than a stylised diagram: to me, it serves to magnify his greatness. Why would I worship a God that would design cell-adhesion molecules to be so inflexible as to hold a singular shape? Is it not more amazing that laminins were designed with the ability to change their shape to do their job?


2. We don’t need laminins to be cross-shaped to affirm the truth of Colossians 1.

The biggest concern for me is when Christian T-shirts, blogs and facebook threads conclude that Colossians 1:17 directly refers to the laminin molecule. This divorces the verse from the rest of the section’s context (Col. 1:15-20), where one can read a moving description by the Apostle Paul of the lordship of Christ in relation to both creation and redemption. What we can draw from verse 17 is that Christ does continually sustain his creation, preventing it from falling into chaos and disintegration (Heb. 1:3). What we can’t conclude from this verse is that Christ is primarily using vaguely-cross-shaped molecules to hold all things together. Indeed in Hebrews 1:3, we see that Christ does this instead by “the word of his power” – not just Giglio’s stylised version of laminin molecules.

If God really wanted us to affirm the truth in Colossians 1 by stating that laminins were his signature, He would have made this clear in scripture. In the meantime, Colossians 1:17 is not just about laminins. I’d encourage everyone to read the passage in its entirety, particularly through to verses 21-23 which ties up the passage beautifully with the offer of Christ’s reconciliation through “the hope of the gospel”.

In the next post (if time permits) I’ll share more of my thoughts on this topic, and ask some tougher questions.

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3 Responses to “A word about laminins (part 1)”

  1. Good post, William. I let out a groan when I was watching the dvd and Giglio did the laminin thing. More so because he seems to me to be a pretty good guy, and a decent teacher too. But I suppose it’s human nature to look for a magic bullet. He showed some pictures of cross-shaped galaxies too.


  2. Yeah I remember the cross-shaped galaxy thing. I suspect the Ignatius video (http://www.youtube.com/watch?v=wLGLBVSpBzY) was poking fun at this when the youth pastor photoshopped Jesus’s face on a galaxy!


  3. Yeah I loved that!


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